Systems Biology Provides First Global Analysis Of Prion Disease In A Mouse Model (Medical News Today) Researchers at the Institute for Systems Biology (ISB) in Seattle and the McLaughlin Research Institute in Great Falls, Montana, published in Molecular Systems Biology a ground-breaking study which modeled the progression of degenerative brain diseases, one of which is "mad cow disease," that are caused by misfolded proteins called "prions". The paper can be accessed at http://www.nature. [News Source]